SNP Tagging Carlson-Method
HelixTree has SNP tagging capability available from the LD plot (Figure 1), based on the Carlson method. This method is based on the R² LD statistic, and determines groupings of markers which are in tight correlation with an individual marker or markers (tagging markers) within the grouping. Markers whose minor-allele frequency is not sufficiently high are not considered for designation as tagging markers.
Figure 1. Running SNP tagging from LD Plot.
SNP Tagging spreadsheet
