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Genetic Association Tests Overview

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18.1 Genetic Association Tests Overview

The HelixTree Genetic Association Test window offers a straightforward way of testing for genetic association against either cases vs. controls or quantitative traits using one or more statistical measures under any one of several genetic model assumptions.

In addition, for most genetic models, the HelixTree Association Test window offers stratification correction using one or more of the following methods:

  • Principal Components Analysis (“the EIGENSTRAT method”)
  • Genomic Control

Some tests have variations which use any missing data values you may have in your genotypes as predictors. Please see 18.4 for a discussion of the subject of including missing values in tests performed by the HelixTree Association Test module.

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