Pharmacogenomic (PGx) analysis empowers researchers and clinicians to tailor drug therapies based on a patient’s genetic profile, but not all regions of the genome are easy to interpret. Genes like CYP2D6 and HLA-A are tricky when it comes to rendering diplotype calls. This is due to a number of factors including high polymorphism, structural variations (including copy number variants), and… Read more »
Next-generation sequencing (NGS) embodies the process of elucidating the signal from the noise. Given the genetic data of a patient, ranging from a targeted gene panel to a whole genome, a healthcare provider’s onus is to glean as much actionable information from the detected variants. As the field of NGS has grown and improved, the scope of available genomic markers… Read more »
When prescribing medications, it is important that healthcare providers be aware of any potential risks a drug may pose to a patient. Pharmacogenomics (PGx) is the field of study that informs how a person’s genetic makeup affects their response to medications. This field is an important part of precision medicine and tools like VarSeq PGx (VSPGx) enable clinicians to use… Read more »
