2019 has been an exceptional year for our organization highlighted by the launch of our VSClinical AMP workflow and being named to the 2019 Inc. 5000 list of fastest-growing private companies.
September Newsletter
Fast Annotations Around the Globe: Our Sydney and Frankfurt Data Mirrors

Fast Annotations Around the Globe: Our Sydney and Frankfurt Data Mirrors
By Gabe Rudy
VP of Product & Engineering

If you have watched this blog over time, it would be no surprise that Golden Helix invests a lot in curating genomic annotations for use with our clinical and research analysis products. Often, we spend considerable time on the attention to detail necessary to ensure the best experience for any data source by cleaning, normalizing, documenting and then distributing it through our data annotation server... Read More

VS-CNV; Golden Helix’s solution to replace traditional methods

VS-CNV; Golden Helix’s solution to replace traditional methods
By Eli Sward, Ph.D
Field Application Scientist

Copy Number Variation (CNV) is a type of structural variation in which sections of the genome are duplicated or deleted. Although CNV events are rare in the human population, constituting approximately 10% of the human genome, they are also associated with being causal mutations for disease phenotypes. Because of this, it is important for clinical and research settings to identify CNV events in their samples or datasets... Read More

Golden Helix's End-to-End Architecture for Clinical Testing Labs

Golden Helix's End-to-End Architecture for Clinical Testing Labs
By Gabe Rudy
VP of Product & Engineering

As clinical genetic tests have been adopted as a critical enabler of precision medicine, the number of tests offered by clinical labs and the volume of tested patients has grown by orders of magnitude in the past five years. The Gene Testing Registry, managed by the NIH, documented a rise from 13,000 to 60,000 tests offered in the US market... Read More

Using the K-Fold Cross-Validation Statistics to Understand the Predictive Power of your Data in SVS

Using the K-Fold Cross-Validation Statistics to Understand the Predictive Power of your Data in SVS
By James Grover
Senior Software Engineer

Using the K-Fold Cross-Validation Statistics to Understand the Predictive Power of your Data in SVS In cross-validation, a set of data is divided into two parts, the “training set” and the “validation set”. A model for predicting a phenotype from genotypic data and (usually) some fixed effect parameters is “trained” using the training set—that is, the best value(s) of the... Read More

CEO Corner
New eBook: Clinical Variant Analysis for Cancer
2019 has been an exceptional year for our organization highlighted by the launch of our VSClinical AMP workflow and being named to the 2019 Inc. 5000 list of fastest-growing private companies. With 2020 almost upon us, we are preparing for our organizations’ goals for the new year which I look forward to sharing with everyone on our blog in January. As always, thank you for your continued support and partnership this year. Our team sends everyone best wishes for a happy holiday season and a new year filled with health, happiness, and spectacular success.
Upcoming Webcast

Building Secure Analysis and Storage Systems with Golden Helix
January 15, 2020 | 12:00 PM Eastern

Genetic testing labs deal with personal data in categories with the highest level of security requirements: personal identity and medical records. Given the liability and risk associated with a breach of this secure information, it is not surprising that many labs and institutes that aggregate genomic data prefer if not require on-premise analysis and storage solutions.

Register
Customer Success

Congratulations to all of our customers who have published this month! To highlight just a few:

"GBLUP Analysis Predicted Fertility Phenotypes of Crossbred Bulls Using Data from Brahman and Tropical Composite" - Marina Fortes & Colleagues, University of Queensland / Presented at the Association for the Advancement of Animal Breeding & Genetics, 2019 Conference 

"Longitudinal Phenotypes Improve Genotype Association for Hyperketonemia in Dairy Cattle" -  Heather Huson & Colleagues, Cornell University / Published in MDPI Animals

"Genetic Dissection of Maternal Influence on In Vivo Haploid Induction in Maize" -  Sudha Nair & Colleagues, CIMMYT / Published in The Crop Journal

About Golden Helix

Golden Helix has been delivering industry-leading bioinformatics solutions for the advancement of life science research and translational medicine for over 20 years with 1,000s of users around the world. Their innovative technologies and analytic services empower scientists and healthcare professionals at all levels to derive meaning from the rapidly increasing volumes of genomic data produced from NGS sequencers and microarrays. With their solutions, hundreds of the world's top hospitals, testing labs, pharmaceutical, biotech, and academic research organizations can harness the full potential of genomics to identify the cause of disease, improve the efficacy and safety of drugs, develop genomic diagnostics, and advance the quest for personalized medicine.