GenomeBrowse focuses on displaying data in a form that helps you quickly and easily understand what the data is saying. Each variant and its surrounding context is displayed in extraordinary detail.
To help you get the most out of your data, GenomeBrowse provides:
A large annotation library curated by Golden Helix is available on demand from our servers eliminating the need to waste time downloading gigabytes of files to see if an annotation exists at a specific position. If you need offline access to any annotation, it can also be downloaded.
Hosted annotations include:
If your alignment data is stored in the cloud or an internal network, GenomeBrowse provides the ability to easily stream it when given either the direct URL or the URL to a containing directory.
GenomeBrowse is flexible enough to handle a wide variety of file formats. Many formats can be viewed in multiple ways to highlight what is important in the data. Supported formats include:
GenomeBrowse can display data from both NGS and GWAS studies as long as it can be represented in any of our supported formats or convertible with our powerful Convert Wizard. Coverage information is generated automatically and in the background for BAM and VCF files so that you don't have to use a different tool just to view your data.
A wide variety of reference sequences ship with GenomeBrowse including GRCh37 g1k for Humans, Bos taurus, Ovis aries, Gallus gallus, and Baker's yeast. Custom reference sequences can be added for your species using the Convert Wizard which can transform numerous file formats into a GenomeBrowse reference.
GenomeBrowse is different than other genome browsers on the market:
GenomeBrowse displays the raw data the variant caller used to make its decision. You can quickly spot systematic strand bias, alignment mismatches due to InDels, or issues with nearby read coverage that can produce false-positive variants.
Whether you are conducting a case/control study, analyzing a trio, or many independent samples, GenomeBrowse can display all your alignment data. Looking at all your samples in one view can help you spot contextually relevant findings.
Now you can have visual confirmation for the above issues and more.
GenomeBrowse ships with first-class, native integration with Evernote. You can easily save your genomic findings in GenomeBrowse with bookmarked regions and screenshots to any of your Evernote notebooks. These notes can be shared with colleagues and collaborators so that getting feedback is just a click away. Notes can be tagged and then easily searched, making your GenomeBrowse projects as organized as you want to make them. Read more about the Evernote integration on "Our 2 SNPs..." »
GenomeBrowse can be controlled programmatically via HTTP so that you can quickly generate the visualizations that interest you via remote access. Use the built-in automation functionality to integrate GenomeBrowse into your existing workflow with ease and flexibility.
Easily generate publication quality plots that showcases how your data clearly supports your discoveries. Plots are rendered to ensure that your data looks as good in print as it did on screen. All user interface elements that might distract from your data are stripped from the image. Colors are highly customizable and a cross-plot anchor can be set to draw attention to the most relevant discoveries.
GenomeBrowse runs as a native desktop application on your computer. No longer do you have to sacrifice speed and interface quality to obtain a consistent cross-platform experience. It was developed with performance in mind to deliver a faster and more fluid browsing experience than any other genome browser available.
GenomeBrowse is also integrated in the powerful Golden Helix SNP & Variation Suite (SVS) analysis platform. If love the visualization experience of GenomeBrowse, check out SVS for filtering, annotating, and analyzing your data prior to utilizing the same visualization interface. Learn more about upgrading from GenomeBrowse to SVS »
Release notes are available in the GenomeBrowse manual
Individuals from commercial companies are free to download, install, and use GenomeBrowse inside their organization without any cost or restrictions except the general use restrictions outlined in the End-User License Agreement for GenomeBrowse. If a company is interested in adding GenomeBrowse as a "value add-on" to their product, including but not limited to links within the product to GenomeBrowse and/or full instances of the software, and/or if the organization intends to use GenomeBrowse for any monetary or other business benefit, they must contact Golden Helix at email@example.com or 406-585-8137 for a separate licensing agreement.