Video Tutorial: Genetic Association in Complex Disease

Created: January 19, 2011  |  Runtime: 1 Hour, 36 Minutes

Level: Fundamentals  |  Version: SVS 7.4

The following video tutorial covers a SNP analysis workflow on a whole-genome scale (while highlighting new SVS 7.4 functionality) including analysis preparation, data editing and manipulation, sample quality assurance (call rate, gender check, outliers in autosomal heterozygosity, reducing SNPs to informative subset, cryptic relatedness, and population stratification), SNP quality assurance, genotype association analysis based on a binary trait (including q-q plots and manhattan plots), genotype association analysis based on a quantitative trait, and regression analysis. This recording is from a live demonstration given by Dr. Bryce Christensen on January 19, 2011.

This tutorial uses an SVS project bundle which can be downloaded so that you can follow along. There is also a written handout.

Download	Files	Size	Type	Description
	SVS_SNP_GWAS_Training.zip	108 MB	Data	SVS project file with genotype data and simulated phenotype
	SNP_GWAS_Tutorial.pdf	2 MB	Handout	Written tutorial in PDF format

Click below to begin video. The chapters at left can be used to navigate to a section.