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  1. questionQuantitative Haplotype Association Test and HTR in SVS7
    Q: How do I perform haplotype association tests if I have a quantitative dependent variable? Similarly, how do I perform haplotype trend regression in SVS 7? A: SVS 7 makes performing haplotype association tests easy if there is a binary dependent variable. It is still possible to perform assoc ...
  2. questionHow do I perform genotype regression using a specific genetic model (additive, dominant, or recessive) with covariates?
    SVS 7 requires that predictors in a regression model be numeric, not genotypic (A_A, etc.). In order to perform regression analysis on genotypes, they must first be re-coded as numeric values based on a chosen genetic model (additive, dominant or recessive). Click the link below to download ins ...
  3. questionHow does permutation testing work in the Regression Module?
    The permutation of p-values in the regression module will permute the p-value for the overall haplotype trend regression (HTR) test x-number of times. The permutation changes the order of the dependant variable randomly, then runs HTR test again doing the moving window computation on all SNPs. A ...

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