How VarSeq Supports Inherited Trait Discovery & Carrier Screening

As we gather around the table this season, many of us reflect on family and where we come from, what connects us, and what we pass on. In the field of genetics, these same concepts are explored through the study of inheritance and carrier screening. NGS analysis tools, such as VarSeq, enable users to transition from raw genomic data to meaningful insights that help explain why certain traits or health conditions are inherited within families, or to assist new couples in planning with confidence.

Why These Tests Matter

Just like traditions, stories, and recipes, our genetic information is something we inherit and pass along. Understanding that inheritance can be empowering. Family-based analyses can:

Leveraging VarSeq for Family Based Analyses

VarSeq offers intuitive workflows designed for analyzing families of all sizes, from trios to extended pedigrees, and couples carrier screening workflows. These workflow templates help users uncover shared variants, highlight inheritance patterns such as de novo variants, compound heterozygosity between small variants or across small variants and copy number variants, recessive homozygous traits, dominant or X-linked traits.

These workflows help genetics labs to identify findings that may be relevant to inherited conditions on behalf of their clients or reassure couples about what genetic traits, if any, they may pass on to their offspring.

This season reminds us of the importance of family, from grandparents to grandchildren and everyone in between. With VarSeq’s family analysis and carrier screening capabilities, users can explore the genetic stories that connect loved ones and support informed choices for generations to come.
If you’d like to learn more or explore these workflows in practice, our team is always happy to help at [email protected].