Industry-Leading Genomic Data Analysis Software

Analyze your Next-Gen Sequencing data in one, complete solution from FASTQ to a clinical report.


In business for 20 years and cited in 1,300+ publications, we are proud to support over 20,000 users in more than 400 institutions worldwide.


Our entire clinical pipeline consists of software products that are deeply integrated with each other. In addition, we provide automation capabilities that are crucial in high-throughput testing environments.


No per-sample charges! You will save money with our annual subscription model. Licenses include unlimited training and support to ensure success.

Popular Products

SNP & Variation Suite

SNP & Variation Suite is a powerful analytic tool that allows biologists and other researchers to easily perform complex analyses and visualizations on genomic and phenotypic data.

  • GWAS & SNP Analysis
  • Large-N DNA-Seq Analysis
  • Genomic Prediction
  • Copy Number Analysis
  • RNA-Seq Analysis

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VarSeq is an intuitive, integrated software solution for tertiary analysis. With VarSeq you can automate your workflows and analyze variants for gene panels, exomes, and whole genomes.

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Built on the same algorithms of Varseq, VSWarehouse is a scalable, multi-project warehouse for NGS variant call sets, clinical reports, and catalogs of variant assessments.

  • Fully Integrated with VarSeq Workflows
  • Scalable Technology
  • Organize Samples into Projects
  • Centralized Clinical Report Hosting
  • Create Variant Assessment Catalogs

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Support for Various Industries

Customer Testimonials

Benjamin Darbo, Ph.D

University of Iowa

Dr. Benjamin Darbro, Director of Shivanand R. Patil Cytogenetics and Molecular Laboratory

“VarSeq had everything we were looking for with regards to annotation, filtering sources and an actual visual browser within the software itself. However, what really set it apart in retrospect is how intuitive it is.”

Read Darbro's Case Study

Heather Huson, Ph.D

Cornell University

Dr. Heather Huson, Professor of Dairy Cattle Genetics, Odyssey DNA Lab

"The huge benefit of SVS is it's user-friendly, and you can basically visualize your results in the same program. You don't have to spend nearly as much time manipulating data and results to get it in the right input and output formats."

Read Huson's Case Study

Hela Azaiez, Ph.D

University of Iowa

Dr. Hela Azaiez, Associate Research Scientist, Molecular Otolaryngology and Renal Research Laboratories

“SVS opened so many doors for my research. It allowed me to explore new ideas. It allowed me to do stuff I never thought was even possible to do in that amount of time so that I could test so many hypotheses. All that I had to do is click a button.”

Read Azaiez's Case Study

Upcoming Webcast

Whole Genome Trait Association in SVS

July 15, 2020 | 12:00 PM EDT

Golden Helix’s SNP & Variation Suite (SVS) has been used by researchers around the world to do trait analysis and association testing on large cohorts of samples in both humans and other species. As Next-Generation Sequencing of whole genomes becomes more affordable, large cohorts of Whole Genome Sequencing (WGS) samples are available to search for additional trait association signals that were not found in array-based testing. In fact, recent papers have shown that WGS analysis using advanced GREML (Genomic Relatedness Restricted Maximum Likelihood) techniques is able to outperform micro-array based GWAS methods in the analysis of complex traits and proportion of the trait heritability explained.

Our latest update release of SVS has expanded the exiting maximum likelihood and GRM methods to support these new techniques. We have also enhanced various other association testing and prediction methodologies. Join us for our upcoming webcast where we will showcase:

  • Newly supported analysis workflow for whole genome variants using LD binning and enhanced GBLUP analysis
  • Enhanced gender correction using REML
  • Additional capabilities for genomic prediction and phenotype prediction

We are continually improving our products based on our customer’s feedback. We are looking forward to highlighting the exciting new features and select enhancements we have made in this upcoming webcast.