Enable precise molecular diagnosis and therapy selection through comprehensive tumor profiling, guideline-driven variant interpretation, and therapy-matched reporting.
Evidence Levels
Standardized AMP evidence ranking from FDA-approved to pre-clinical studies.
Integrated genomic signatures for immunotherapy response prediction.
Expert-curated clinical interpretations and therapy associations.
Golden Helix enables labs to deliver more than just a list of variants. By aggregating global knowledge bases and oncology guidelines, VSClinical provides actionable intelligence at the point of interpretation.
Connect somatic mutations directly to FDA, EMA, and NCCN-recognized therapies with detailed drug descriptions and resistance profiles.
Automatically match patients to ongoing trials from ClinicalTrials.gov based on their specific tumor profile, location, and phase requirements.
Automate the tiering of somatic variants according to the joint AMP/ASCO/CAP guidelines (Tiers I-IV) for clinical reporting.
Modern oncology requires more than SNV detection. Our platform enables the integrated analysis of small variants, structural variations, and complex genomic signatures.
Identify amplification and deletion events that drive oncogenesis. Integrated LOH analysis helps distinguish copy-neutral events and somatic-only changes.
Somatic CNV DetectionDetect complex structural variants and gene fusions like ALK or BCR-ABL1. Evaluate domain/exon boundaries and tier evidence across tumor types.
CNV & SV AnalysisCalculate Tumor Mutational Burden and Microsatellite Instability directly from NGS data to assess suitability for immune checkpoint inhibitors.
Reduce manual research burden by leveraging Golden Helix CancerKB™ alongside community databases. Our platform aggregates evidence from multiple sources to provide a unified view of clinical relevance.
Professionally curated interpretations, treatment links, and trial associations tailored to specific tumor types.
Aggregation of community-curated evidence for variant actionability and clinical outcomes.
Real-time matching to clinical trials with full inclusion and exclusion criteria details.
Explore our featured articles and webcasts on precision oncology and somatic interpretation.
Join leading oncology centers worldwide using Golden Helix to deliver actionable cancer genomics insights and therapy-matched reporting.