For many of you this might be a busy week with school starting up again! However, even though school is just starting, many of our customers have been publishing all summer long. Here are a few highlights from our most recent publications this August:
- Evaline Ibeagha-Awemu and Xin Zhao of Agriculture and Agri-Food Canada, along with colleagues, published High density genome wide genotyping-by-sequencing and association identifies common and low frequency SNPs, and novel candidate genes influencing cow milk traits in Nature’s Scientific Reports. This study used high throughput genome wide genotyping-by-sequencing to generate 515,787 SNPs which were used in a GWAS of 44 milk traits.
- Abderrahim OUssalah of the Henri Poincare University and colleagues published Cystathionine β-synthase genetic variant rs2124459 is associated with a reduced risk of cleft palate in French and Belgian populations in the Journal of Medical Genetics which looked for potential genetic variants associated with orofacial cleft using a gene panel of one-carbon metabolism.
- A genome-wide scan of copy number variants using high-density SNPs in Brown Swiss dairy cattle was published in Livestock Science by Alessandro Bagnato and Marlies Delzal of the University of Milan and colleagues. The purpose of the study was to investigate CNVs in samples of Brown Swiss Cattle, and it was the first comprehensive genomic analysis of this breed based on the Illumina Bovine SNP chip.
- David Tester of Mayo Clinic and colleagues published Whole Exome Sequencing, Familial Genomic Triangulation, and Systems Biology Converge to Identify a Novel Nonsense Mutation in TAB2-encoded TGF-beta Activated Kinase 1 in a Child with Polyvalvular Syndrome in Congenital Heart Disease, which used whole exome sequencing of a family trio to identify a genetic cause for polyvalvular syndrome.
- Tarrant Cummins of Monash University and Mauricio Arcos-Burgos of the Australian National University published Rare DNA variants in the brain-derived neurotrophic factor gene increase risk for attention-deficit hyperactivity disorder: a next-generation sequencing study in Molecular Psychiatry. They performed a large scale next-generation targeted sequencing study of ADHD to determine if rare variants might explain a portion of missing heritability.