Tag Archives: twist exome

Golden Helix VarSeq in Action – P715: Analyzing performance of the Twist exome with CNV backbone at various probe densities leveraging Golden Helix VS-CNV

         March 22, 2024

Recently, at ACMG 2024, we unveiled a collaborative research project with Twist Biosciences. By utilizing Twist Bioscience enhanced Exome 2.0 Plus Comprehensive Exome Spike-In capture panel with added backbone probes, we developed a multi-modal CNV caller designed specifically for target-capture NGS data to detect single-exon to whole-chromosome aneuploid CNV events. We are proud to say that from Golden Helix, Andreas… Read more »

Analyzing Performance of the Twist Exome with CNV Backbone at Various Probe Densities Leveraging Golden Helix VS-CNV Recap

         February 22, 2024

In our recent webcast, we unveiled the integration of the Twist Bioscience Exome 2.0 Plus Comprehensive Exome Spike-in capture panel with VS-CNV, marking a significant advancement in genetic diagnostics. By addressing the limitations of standard exome kits that miss vast genomic regions, our enhanced panel introduces ‘backbone’ probes for comprehensive genomic coverage. This innovation enables the detection of CNVs, LOH,… Read more »