About this webinar
Recorded On: Wednesday, July 10, 2019
Before accessing the clinical evidence associated with a specific variation, one must establish that the variant is likely to be a driver mutation, which generates functional changes that enhance tumor cell proliferation. In this webcast, we will discuss VSClinical’s capabilities for determining the oncogenicity of a variant. This will include a deep dive into our oncogenicity scoring system and a discussion of the various criteria used to distinguish driver mutations from benign variations and variants of uncertain significance.
What you will learn in this webcast:
- How to evaluate the oncogenicity of a variant in VSClinical
- What evidence to consider when classifying LoF variants
- How to examine the in-silico evidence for missense variants
- How to evaluate a variant's rate of occurrence in somatic catalogs
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